学习与工作经历：

2025-01 至今, 山东大学齐鲁医院,脊柱外科副主任，博士后导师

2022-12 至今，山东大学齐鲁医院, 副主任医师，临床副教授

2022-12 至今，山东大学高等医学研究院，研究员，硕士研究生导师

2018-07至2020-12，天津医科大学总医院骨科，主治医师，讲师

2017-06至2018-04，UniSA(澳大利亚)，高级访问学者

2014-09至2017-06，天津医科大学骨外科学，博士

2011-07至2014-09，天津市泰达医院骨科，住院医师

2008-09至2011-06，天津医科大学骨外科学，硕士

2003-09至2008-06，河南大学医学院临床医学，学士

研究方向：

主要从事退变、微创、人工智能脊柱外科、脊柱脊髓损伤的基础研究及临床诊治工作。主要研究方向为脊髓损伤分子病理机制、智能生物材料组织修复、干细胞及类器官移植组织修复技术。

学术/社会兼职：

担任国际神经修复学会（IANR）青年委员、国际神经修复学会脊髓损伤基础研究分会副主任委员、中国解剖学会骨科解剖学分会委员、山东省医学会骨科学分会神经修复学组副组长等学术兼职。担任AM、CDD、CEJ等期刊审稿人，担任Exploration、Research等知名期刊青年编委。

获奖荣誉：

荣获山东省科技进步发明奖一等奖、天津市科技进步特等奖、天津市科技进步一等奖、天津市青年后备人才、第十届国际神经修复学协会(IANR)年会Riseman青年奖一等奖等奖项。

本科生课程：

《外科学实验课》

研究生课程：

（1）82572730，生物-电化学耦合工程化ECM多重调控脊髓损伤内源性修复的实验研究，国家自然科学基金委员会面上项目，2026-01-01至2029-12-31，49万元，主持

（2）81702147，雪旺细胞外泌体介导PTEN/AKT/mTOR信号通路修复脊髓损伤后肌萎缩的实验研究，国家自然科学基金委员会青年科学基金项目，2018-01-01至2020-12-31，20万元，主持

（3）tsqn20221168，人才项目，山东省卫生健康委员会（泰山学者青年专家） 2022-11至2025-06，100万元，主持

（4）S21DYZD4133，电化学自适应神经中继站修复脊髓损伤，天津市科技局多元投入基金项目重点项目，2021-10-01至2024-09-30，20万，主持

（5）2024YFC3607000, 高龄脊柱融合手术加速康复体系构建与应用示范, 国家重点研发计划(主动健康和人口老龄化科技应对), 2025-5至2028-4，1000万，参与

1.Mingshan, Liu*; Wencan, Zhang*; Shuwei, Han*; Dapeng, Zhang; Xiaolong, Zhou; Xianzheng, Guo; Haosheng, Chen; Haifeng, Wang^#; Lin, Jin^#; Shiqing, Feng^#;Zhijian, Wei^#.Multifunctional Conductive and Electrogenic Hydrogel Repaired Spinal Cord Injury via Immunoregulation and Enhancement of Neuronal Differentiation.Advanced Materials. 2024 Feb 2:e2313672.(Correspoonding Author, IF 26.8)

2.Wencan Zhang*, Mingshan Liu*, Jie Ren*, Shuwei Han, Xiaolong Zhou, Dapeng Zhang, Xianzheng Guo, Haiwen Feng, Lei Ye, Shiqing Feng^#, Xizi Song^#, Lin Jin^#,Zhijian Wei^#.Magnetic Nanoparticles and Methylprednisolone Based Physico-Chemical Bifunctional Neural Stem Cells Delivery System for Spinal Cord Injury Repair.Advanced Science. 2024 March 22 advs.202308993.(Correspoonding Author, IF 14.1)

3.Zhu, Bin*; Gu Guangjin*; Ren, Jie*; Song,Xiaomeng*; Li, Junjin; Wang, Chunyan; Zhang, Wencan; Huo Yanqing; Wang, Haifeng; Jin, Lin^#; Feng, Shiqing^#;Wei , Zhi-Jian^#. Schwann Cell-Derived Exosomes and Methylprednisolone Composite Patch for Spinal Cord Injury Repair.ACS Nano. 2023 Nov 10. (Correspoonding Author, IF 16.0)

4.Xiangzhen Kong*, Rui Hu*, Peng Zhang*, Qi Li, Kangle Song, Hanwen Gu, Jihui Zheng, Shen Liu, Liang Liu, Lin Jin^#, Lei Cheng^#, Chengwei Li^#, andZhijian Wei^#. Modulating Macrophage–Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration.Advanced Science. 2025 Jun 17 advs.202507178.(Correspoonding Author, IF 14.1)

5.Bin Chen*, Hang Li*, Hong Zhang*, Junyan Xu, Shuofu Liang, Ghazal Shokraneh, Hecheng Ma, Gang Wang^#, Junhao Lin^#,Zhijian Wei^#. Dual-network hydrogel loaded with octreotide promotes diabetic wound healing by inhibiting cGAS-STING pathway.Chemical Engineering Journal, 526 (2025) 170675. (Co- Correspoonding Author, IF 13.2)

6.Chunyan Wang*；Peng Zhang*；Yuan Pan*；Chuan Huang；Ruike Zhang；Guangchen Yang；Jihui Zheng；Chunxiao Wan^#；Zhijian Wei^#.Multifunctional conductive stem cell delivery hydrogel combined with low-frequency pulsed electromagnetic fields for spinal cord injury repair.Materials & Design. 2024 246 (2024) 113356. (Correspoonding Author, IF 7.9)

7.Lei Zhang*；Panyong Zhu*；Xiaolin Pan；Bei Zhao；Xiaojin Li；Kaiwen Liu；Rui Hu；Ling Zha；Guohua Jia^#；Chengwei Li^#；Lin Jin^#；Zhijian Wei^#.Composite supramolecular hydrogel for osteoarthritis and cartilage repair enables localized and sustained drug delivery.Materials & Design.2025 Jun;254, 114066.(Correspoonding Author, IF 7.9)

8.Bin Chen*；Hang Li*；Yuliang Sun*；Yuhua Li；Parisa Anvari；Ghazal Shokraneh；Menglin Cong；AmirMahdi Saeidi；Hecheng Ma；Tian Li^#；Gang Wang^#；Junhao Lin^#；Zhijian Wei^#.Dual-Network QSAZ@VPH hydrogel-mediated verapamil treatment improved recovery of diabetic ulcer through inhibiting mitochondrial oxidative stress and enhancing angiogenesis,Materials & Design.2025 Jun;256, 114252.(Correspoonding Author, IF 7.9)

9.Gu Guangjin*; Zhu Bin*; Ren Jie*Shi Zhongju ; Feng Shiqing^#,Wei , Zhijian^#,Multiple mechanisms of curcumin targeting spinal cord injury,Biomedicine & Pharmacotherapy.2023 Mar;159:114224.(Correspoonding Author, IF 7.5)

10.Zhijian Wei*, Susu Huang*, Wencan Zhang*, Jiayao Wen, Xiaolong Zhou, Wei He, Xiaoye Yang, Haifeng Wang, Guangxi Zhai, Bin Shi^#, Lin Jin^#, Dachuan Wang^#, Shiqing Feng^#, Lei Ye^#,Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury,Advanced Science. 2025 Nov 12:e10976.(Correspoonding Author, IF 14.1)

11.Dapeng Zhang*, Xiaolong Zhou*, Chenxi Zhao*, Shuwei Han, Xianzheng Guo, Haosheng Chen, Wenzhao Wang, Wencan Zhang, Mingzheng Chang, Qingliang Ma, Yunhao You, Mingshan Liu, Xinyu Liu^#, Zhijian Wei#, Xiaohong Kong^#, Shiqing Feng^#.Spatiotemporal-controlled ultrasound-driven Li-PDA@ZnO nanoparticles promote neural stem cell differentiation synergy with biohydrogel repair spinal cord injury.Bioactive Materials, 55 (2026) 446–463. (Co- Correspoonding Author, IF 20.3)

12.Xiangzhen Kong*, Hanwen Gu*, Yuanqiang Zhang*, Qunbo Meng, Qi Li, Kangle Song, Yanlin Li, Kaiwen Liu, Zhenchuan Liu, Rui Hu, Haoxi Zhai, Tian Li, Zemin Ling^#,Zhijian Wei^#, Fuxin Wei^#, and Lei Cheng^#.𝜷-Mangostin Attenuates TET2-Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration.Advanced Science. 2025 Jun 25 advs.202505077.(Correspoonding Author, IF 14.1)

13.Boyang Xu, Ling Li, Qian Wei, Yuli Wang, He Huang, Tao Pang^#,Zhijian Wei^#, Guoqing Zheng^#，Yue Li^#. Cholesterol metabolism on stem cell fate determination: a frontier horizon.Stem Cell Research & Therapy. Article number: 561 (2025). (Correspoonding Author, IF 7.3)

14.Haifeng Wang*, Wencan Zhang*, Yiming Ren*, Jincheng Lu, Shen Liu, Liang Liu, Peng Zhang,Zhijian Wei^#, Dachuan Wang^#, Liang Chen^#. Ultrasound-driven piezoelectric hydrogel enhances Schwann/neural stem cells Co-transplantation for spinal cord injury repair.Materials & Design. 2025 May; 253, 113842. (Co-Correspoonding Author, IF 7.9)

15.Yiming Ren*, Bo Li*, Bo Yang*, Baoyou Fan*, Shenghui Huang, Guidong Shi, Liang Liu^#,Zhijian Wei^#, Shiqing Feng^#. Single-cell RNA sequencing of the post-spinal cord injury dorsal root ganglia in cynomolgus monkeys: elucidation of the cellular immune microenvironment of the central nervous system.Neural Regeneration Research, 2025 Mar 25. (Co- Correspoonding Author, IF 6.7)

16.Junjin Li*，Hongda Wang*，Yuanquan Li*，Chunzhen Wang*，Haiwen Feng，Yilin Pang，Jie Ren，Chuanhao Li，Erke Gao，Dejing Zhang，Dunxu Hu，Pengtian Zhao，Han Ding，Baoyou Fan，Tao Zhang，Xiaomeng Song，Zhijian Wei^#，Guangzhi Ning^#，Yongqiang Li^#，Shiqing Feng^#.Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury.Bioactive Materials, 45 (2025) 534–550. (Co- Correspoonding Author, IF 20.3)

17.Lei Liang*, Hongda Wang*, Linfa Li, Ding Lin, Bingyan Guo, Mengmeng Yao,Zhijian Wei^#, Hong Zhang^#, Junjie Li^#. Microparticle deposition induced asymmetric adhesive hydrogel for suture-less gastric trauma treatment.Chemical Engineering Journal, 2024 April Volume 485, 1, 150086. (Co- Correspoonding Author, IF 13.2)

18.ShuweiHan*；Dapeng Zhang*；Yanbing Kao*；Xiaolong Zhou；Xianzheng Guo；Wencan Zhang；Mingshan Liu；Haosheng Chen；Xiaohong Kong^#；Zhijian Wei^#；Hong Liu^#；Shiqing Feng^#.Trojan Horse Strategy for Wireless Electrical Stimulation-Induced Zn²⁺Release to Regulate Neural Stem Cell Differentiation for Spinal Cord Injury Repair.ACS Nano. 2024 Nov 11. (Correspoonding Author, IF 16.0)

19.Teng Zhang, Wenhao Zhou, Wanliang Yang, Jingwei Bi, Hao Li, Xianlei Gao, Baoliang Zhang, Guidong Shi, Ka Li,Zhijian Wei^#, Xin Pan^#, Shiqing Feng^#. Vancomycin-encapsulated hydrogel loaded microarc-oxidized 3D-printed porous Ti6Al4V implant for infected bone defects: Reconstruction, anti-infection, and osseointegration.Bioactive Materials, 2024 Aug 21:42:18-31. (Co- Correspoonding Author, IF 20.3)

20.Tang, Haoshuai*; Li, Junjin*; Wang, Hongda*; Ren, Jie; Ding, Han; Shang, Jun; Wang, Min;Wei , Zhijian^#; Feng, Shiqing^#. Human umbilical cord mesenchymal stem cell-derived exosomes loaded into a composite conduit promote functional recovery after peripheral nerve injury in rats.Neural Regeneration Research, 2024 Apr;19(4):900-907. (Co- Correspoonding Author, IF 6.7)

21.Li , Jin-Ze* ; Fan , Bao-You* ; Sun , Tao* ; Wang , Xiao-Xiong; Li , Jun-Jin ; Zhang , Jian-Ping ; Gu , Guang-Jin ; Shen , Wen-Yuan; Liu , De-Rong;Wei , Zhi-Jian^#; Feng , Shi-Qing^#,Bioinformatics analysis of ferroptosis in spinal cord injury,Neural Regeneration Research,2023 Mar;18(3):626-633(Co- Correspoonding Author, IF 6.7)

22.Gu Guangjin *; Zhu Bin *; Ren Jie *; Song Xiaomeng; Fan , Baoyou; Ding , Han; Shang , Jun; Wu , Heng ; Li , Junjin; Wang , Hongda; Jinze Li ;Wei , Zhijian^#; Feng , Shiqing^#; Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization,Cell and Bioscience, 2023 Feb 4;13(1):23(Co-Correspoonding Author, IF 6.2)

23.Ren , Jie *; Zhu , Bin * ; Gu , Guangjin * ; Zhang , Wencan; Li , Junjin; Wang , Hongda ; Wang , Min; Song , Xiaomeng^#;Wei , Zhijian^#; Feng Shiqing^#,Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury,Cell Death& Disease,2023 Jan 30;14(1):70(Co- Correspoonding Author, IF 9.6)

24.Yao, Mengmeng^*;Wei, Zhijian*;Li, Junjin; Guo, Zhicheng; Yan, Zhuojun; Sun, Xia; Yu, Qingyu; Wu, Xiaojun; Yu, Chaojie; Yao, Fanglian^#; Feng, Shiging^#;Zhang, Hong^#;Li, Junjie^#. Microgel Reinforced Zwitterionic Hydrogel Coating for Blood-Contacting Biomedical Devices.Nature Communications，2022 Sep 12;13(1):5339.(Co-First, IF 15.7)

25.Wang, Hong-Da*;Wei , Zhi-Jian*; Li , Jun-Jin ; Feng Shi-Qing,Application value of biofluid-based biomarkers for the diagnosis and treatment of spinal cord injury,Neural Regeneration Research,2022 May;17(5):963-971(Co- Correspoonding Author, IF 6.7)

26.Haiwen Feng*, Junjin Li*, Hongda Wang*,Zhijian Wei*, Shiqing Feng^#.Senescence- and Immunity-Related Changes in the Central Nervous System: A Comprehensive Review,Aging & Disease. 2024 Sep 1. (Co-First, IF 6.9)

27.Fan, Baoyou*;Wei, Zhijian*; Feng, Shiqing^#. Progression in translational research on spinal cord injury based on microenvironment imbalance.Bone Research. 2022 Apr 8;10(1):35. (Co-First, IF 15.0)

28.Wei , Zhi-Jian*, Fan , Bao-You*; Liu , Yang* ; Ding , Han; Tang , Hao-Shuai; Pan Da-Yu; Shi , Jia-Xiao; Zheng , Peng-Yuan; Shi , Hong-Yu; Wu , Heng; Li , Ang; Feng , Shi-Qing, MicroRNA changes of bone marrow-derived mesenchymal stem cells differentiated into neuronal-like cells by Schwann cell-conditioned medium,Neural Regeneration Research,2019 Aug;14(8):1462-1469(First, IF 6.7)

29.Li,Ang*;Wei, Zhijian*; Ding, Han*; Tang, Haoshuai; Liu, Yang; Shi, Jiaxiao ; Zhou Hengxing; Feng, Shi-Qing^#; Minimally invasive percutaneous plates versus conventional fixation techniques for distal tibial fractures: A meta-analysis,International Journal of Surgery, 2017 Feb;38:52-60. (Co-First, IF 10.1)

30.Fan , Baoyou^*;Wei , Zhijian^*; Zhou , Xianhu^*; Lin , Wei ; Ren , Yiming ; Li , Ang ; Shi , Guidong ; Hao , Yan ; Liu , Shen ; Zhou , Hengxing ; Feng , Shiqing^#Does vertebral augmentation lead to an increasing incidence of adjacent vertebral failure? A systematic review and meta-analysis,International Journal of Surgery, 2016 Dec;36(Pt A):369-376. (Co-First, IF 10.1)

31.Fan, Baoyou*; Zhou, Xianhu*;Wei, Zhijian*; Ren, Yiming; Lin, Wei; Hao, Yan; Shi, Guidong; Feng, Shiqing^#; Microenvironment Imbalance of Spinal Cord Injury,International Journal of Surgery, 2016 Oct;34:64-72 (Co-First, IF 10.1)

32.Baoyou Fan*,Zhijian Wei*, Xue Yao, Guidong Shi Xin Cheng, Xianhu Zhou, Hengxing Zhou, Guangzhi Ning, Xiaohong Kong, Shiqing Feng^#, Microenvironment Imbalance of Spinal Cord Injury,Cell Transplantation, 2018 Jun;27(6):853-866 (Co-First, IF 3.2引用427次)