学习与工作经历：

2000年-2003年 潍坊医学院硕士研究生；2003年-2006年 山东大学医学院博士研究生；2006年至今 山东大学齐鲁医院；2007年-2010年 山东大学基础医学博士后；2012年-2015年 山东大学化学博士后；2018年 美国堪萨斯大学医学中心高级访问学者。

研究方向：

体部疾病影像诊断、零磁医学，影像组学与人工智能、纳米分子成像

学术/社会兼职：

中国医师协会放射医师分会战略发展工作委员会副组长、中国研究型医院学会肿瘤影像诊断学专业委员会委员、中国医师协会放射医师分会消化学组委员、中华医学会放射学分会分子影像学组委员、山东省放射学分会副主任委员、山东省研究型医院协会影像创新与研究分会主任委员，中国医学影像整合联盟常务理事兼腹部影像专委会委员等。

获奖荣誉：

1、山东省科技进步二等奖（首位）

2、山东医学科技三等奖（首位）

3、山东省科技进步三等奖（第二位）

4、山东生物医学工程学会科学技术一等奖（第四位）

5、齐鲁卫生与健康杰出青年人才

6、全国住院医师规范化培训优秀带教老师

7、山东大学优秀临床教师

8、山东省优秀学位论文指导老师

9、齐鲁医学优秀教师

本科生课程：

断层解剖与医学影像学；医学影像学；消化系统疾病诊疗技术；核医学(双语)

研究生课程：

腹部影像诊断学；医学影像成像原理

国家自然科学基金面上项目

工信部重大项目子课题

山东省自然科学基金重大基础项目

山东省重点研发计划（重大科技创新工程）项目

山东省自然科学基金

1、Wang F, Xu X, Xu J, Li F, Zhang H, Wang L,Yu D*. Exploring the value of multiparametric quantitative MRI in the assessment of pancreatic ductal adenocarcinoma fibrosis grading. Eur Radiol. 2024 Dec 19. doi: 10.1007/s00330-024-11246-w. Epub ahead of print.

2、Sun W, Wang H, Qi Y, Li M, Zhang R, Gao Z*, Cui J*,Yu D*. Metal-Phenolic Vehicles Potentiate Cycle-Cascade Activation of Pyroptosis and cGAS-STING Pathway for Tumor Immunotherapy. ACS Nano. 2024 Aug 27;18(34):23727-23740.

3、An Y, Wei P, Liu L, Yimier R, Peng X, Liu D,Yu D*.Intratumoral calcification on CT assists in distinguishing benign and malignant upper abdomen neoplasm. Postgrad Med J. 2024 Sep 18: qgae118. doi: 10.1093/postmj/qgae118.

4、Zuo L, Hou M, Fan J, Li F, Wang B, Zhao Q, Yang Y,Yu D*. Multiparametric MRI manifestations of the spontaneous intratumoral coagulative necrosis in HCC. Abdom Radiol (NY). 2024 Jul;49(7):2198-2208. doi: 10.1007/s00261-024-04355-z. Epub 2024 May 17. PMID: 38758398.

5、Cui L, Qin Z, Sun S, Feng W, Hou M,Yu D*. Diffusion-weighted imaging-based radiomics model using automatic machine learning to differentiate cerebral cystic metastases from brain abscesses. J Cancer Res Clin Oncol. 2024 Mar 16;150(3):132. doi: 10.1007/s00432-024-05642-4.

6、Li N, Zhang G, Zhan J*,Yu D*. pH-responsive iron-loaded carbonaceous nanoparticles for chemodynamic therapy based on the Fenton reaction. J Mater Chem B. 2024;12(16):3959-3969. Published 2024 Apr 24. doi:10.1039/d3tb02875e

7、Fan J, Zuo L, Li F, Wang B, An Y,Yu D*. Patients with type 2 diabetes mellitus and early diabetic kidney disease exhibit lower computed tomography-measured skeletal muscle attenuation values: a propensity score-matched study. J Ren Nutr. Published online May 20, 2024. doi:10.1053/ j.jrn.2024.04.002

8、Wang B, Zuo L, Fan J, Ji Y, Xu L, Xu M, An Y, Zhang Y, Ji G,Yu D*. Association between higher intermuscular adipose tissue and decreased renal function in patients with systemic lupus erythematosus mediated by insulin resistance. Insights Imaging. 2024 Jun 18;15(1):144.

9、Shuo Shi, Xin-Cheng Mao, Yong-Quan Cao, Yu-Yan Zhou, Yu-Xuan Zhao,De-Xin Yu*. CT Radiomics Features of Abdominal Adipose and Muscle Tissues Can Predict the Postoperative Early Recurrence of Hepatocellular Carcinoma, Academic Radiology,Volume, 2024, 31(4) 1312-1325, https:// doi.org /10.1016/ j.acra.2023.10.001.

10、Wang H，Sun W，Zhou D，Qi Y，Gao Z*，Cui J*，Yu D*. Hydrogel-immobilized nanotherapeutics: Inhibition of protective autophagy to amplify STING signals for postsurgical tumor immunotherapy [J]. Chemical Engineering Journal, 2024, 480: 148211.

11、Zuo L, Tian Z, Zhou B, Hou M, Chen Y, Han P, Ma C, Wu X,Yu D*. Perivascular fat attenuation index value and plaque volume increased in non-target lesions of coronary arteries after stenting. Eur Radiol. 2023 Dec 7. doi: 10.1007/s00330-023-10468-8. Epub ahead of print. PMID: 38057594.

12、Muhammad Shahbaz, Huachun Miao, Zeeshan Farhaj, Xin Gong, Sun Weikai, Wenqing Dong, Niu Jun, Liu Shuwei, Dexin Yu*. Mixed reality navigation training system for liver surgery based on a high-definition human cross-sectional anatomy data set. Cancer Med, 2023 Jan 6. doi: 10.1002/cam4.5583.

13、Shi S, Zhao YX, Fan JL, Chang LY,Yu DX. Development and External Validation of a Nomogram Including Body Composition Parameters for Predicting Early Recurrence of Hepatocellular Carcinoma After Hepatectomy. Acad Radiol. 2023 Oct 3:S1076-6332(23)00277-5. doi: 10.1016/j.acra.2023.05.022. Epub ahead of print. PMID: 37798207.

14、Shi S, Yi H, Zheng Y, Zhao Y, Yu D. Adipose distribution patterns as prognostic factors in patients with HCC: A systematic review and meta-analysis. Eur J Radiol. 2023 Oct;167:111025. doi: 10.1016/j.ejrad.2023.111025. Epub 2023 Aug 2. PMID: 37634440.

15、Lu F, Fan J, Li F, Liu L, Chen Z, Tian Z, Zuo L, Yu D. Abdominal adipose tissue and type 2 diabetic kidney disease: adipose radiology assessment, impact, and mechanisms. Abdom Radiol (NY). 2023 Oct 17. doi: 10.1007/s00261-023-04062-1. Epub ahead of print. PMID: 37847262.

16、F Wang, N Li, W Wang, L Ma, Y Sun, H Wang, J Zhan*,D Yu*. A Multifunctional, Highly Biocompatible, and Double-Triggering Caramelized Nanotheranostic System Loaded with Fe3O4 and DOX for Combined Chemo-Photothermal Therapy and Real-Time Magnetic Resonance Imaging Monitoring of Triple Negative Breast Cancer. International Journal of Nanomedicine, 2023 Feb 19;18:881-897.

17、144. Zhao YX, Xu BW, Wang FQ, Jiang FY, Xu JW, Yu DX. nc-RNA-mediated high expression of CDK6 correlates with poor prognosis and immune infiltration in pancreatic cancer. Cancer Med. 2023 Feb;12(4):5110-5123. doi: 10.1002/cam4.5260. Epub 2022 Dec 1. PMID: 36457244; PMCID: PMC9972169.

18、Zhang G, Li N, Qi Y, Zhao Q, Zhan J*,Yu D*.Synergistic ferroptosis-gemcitabine chemotherapy of the gemcitabine loaded carbonaceous nanozymes to enhance the treatment and magnetic resonance imaging monitoring of pancreatic cancer. Acta Biomater. 2022 Apr 1; 142:284-297.