学习与工作经历：

2019.08至今  山东大学教授

2018.09-2019.07   佛罗里达大学（美国）研究助理授

2015.12-2018.09   佛罗里达大学（美国）博士后

2013.08-2015.11   西北大学（美国）    博士后

2008.08-2013.06   南开大学 生物化学与分子生物学博士

2004.08-2008.06   南开大学 生物科学   学士

研究方向：

胃肠道黏膜疾病（炎症、感染及肿瘤）中免疫系统的应答和调控机制。通过高通量测序等手段，在分子水平探索神经/内分泌系统对黏膜免疫细胞的分子调控机制。

学术/社会兼职：

中国免疫学会青年工作委员会委员、山东省免疫学会常务理事消化免疫委员会主委、山东省医学会科普分会委员。

获奖荣誉：

国家高层次人才引进计划入选者、山东省泰山学者青年专家、山东大学杰出中青年学者。

本科生课程：

研究生课程：

1. 2020YFA0804400 胆汁酸肝肠循环对肠道组织损伤修复的调控机制 国家重点研发计划 2020.12-2025.11 279万 负责人

2. 82071854 天门冬酰胺代谢调控2型先天淋巴细胞影响炎症性肠病的作用及机制研究 国家自然科学基金2021.01-2024.12 70万 负责人

1. Zi-Xiao Zhao, Xi Yuan, Yan-Yan Cui, Jun Liu, Jing Shen, Bi-Ying Jin, Bing-Cheng Feng, Yun-Jiao Zhai, Meng-Qi Zheng, Guan-Jun Kou, Ru-Chen Zhou, Li-Xiang Li, Xiu-Li Zuo, Shi-Yang Li†, Yan-Qing Li†.Melatonin Mitigates Oxazolone-Induced Colitis in Microbiota-Dependent Manner. Front. Immunol. (2022)18;12:783806. (†co-corresponding author)

2. Bi-Ying Jin, Zhen Li, Ya-Nan Xia, Li-Xiang Li, Zi-Xiao Zhao, Xiao-Yu Li, Yan Li, Bing Li, Ru-Chen Zhou, Shi-Chen Fu, Shi-Yang Li†, Yan-Qing Li†. Probiotic Interventions Alleviate Food Allergy Symptoms Correlated With Cesarean Section: A Murine Model. Front. Immunol. (2021)12: 741371. (†co-corresponding author)

3. Li, S., Bostick, J.W., Qu, J., Zhang, B., Urban, J.F., Avram, D., Zhou, L. Aryl Hydrocarbon Receptor Signaling Cell-intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function. Immunity (2018) 49(5): 915-928.

4. Li, S., Heller, J.J., Bostick, J.W., Lee, A., Schjerven, H., Kastner, P., Zhou, L. Ikaros Inhibits Group 3 Innate Lymphoid Cell Development and Function by Suppressing the Aryl Hydrocarbon Receptor Pathway. Immunity (2016) 45(1):185-197.

5. Li, S., Bostick, J.W., Zhou, L. Regulation of Innate Lymphoid Cells by Aryl Hydrocarbon Receptor. Front. Immunol. (2018) 8:1909. doi: 10.3389/fimmu.2017.01909.

6. He, H.*, Li, S.*, Wang, S., Hu, M., Cao, Y., Wang, C. Y. Manipulation of cellular light from green fluorescent protein by a femtosecond laser. Nature Photonics (2012) 6(10):651-6. (*co-first author)

7. Li, S., Du, M., Lan, B., Liu, Y., Yang, Y., Zhang, C., Cao, Y. The N-terminal 20 amino acid region of guanine nucleotide exchange factor Vav1 plays a distinguished role in T cell receptor mediated calcium signaling. J. Biol. Chem. (2013) 288(6):3777-85.

8. Heller, J. J., Schjerven, H., Li, S., Lee, A., Qiu, J., Chen, Z. M., Smale, S.T., Zhou, L. Restriction of IL-22-producing T Cell Responses and Differential Regulation of Treg compartments by Zinc finger transcription factor Ikaros. J. Immunol. (2014) 193(8):3934-46.

9. Ye, J., Qiu, J., Bostick, J. W., Ueda, A., Schjerven, H., Li, S., Jobin, C., Chen, Z. E., Zhou, L. The Aryl Hydrocarbon Receptor Preferentially Marks and Promotes Gut Regulatory T Cells. (2017) Cell reports 21(8):2277-90.

10. Wang, Y., He, H., Li, S., Liu, D., Lan, B., Hu, M., Cao, Y., and Wang, C. All-optical regulation of gene expression in targeted cells. Scientific reports (2014) 4, 5346.

11. He, H., Wang, S., Li, X., Li, S., Hu, M., Cao, Y., Wang, C.Y. Ca2+ waves across gaps in non-excitable cells induced by femtosecond laser exposure. Appl. Phys. Lett. (2012) 100, 173704.

12. Yin, J., Wan, Y., Li, S., Du, M., Zhang, C., Zhou, X., Cao, Y. The distinct role of guanine nucleotide exchange factor Vav1 in Bcl-2 transcription and apoptosis inhibition in Jurkat leukemia T cells. Acta Pharmacol Sin. (2011) 32(1):99-107.