1.Daimin Wei#, Yun Sun#, Han Zhao#, Junhao Yan#, Hong Zhou#, Fei Gong#, Aijun Zhang, Ze Wang, Lei Jin, Hongchu Bao, Shuyun Zhao, Zhuoni Xiao, Yingying Qin, Ling Geng, Linlin Cui, Yan Sheng, Mei Sun, Peihao Liu, Lingling Ding, Hong Liu, Keliang Wu, Yan Li, Yao Lu, Bufang Xu, Bei Xu, Luqing Zhang, Heping Zhang, Richard S Legro,Zi-Jiang Chen*. Frozen versus fresh embryo transfer in women with low prognosis for in vitro fertilisation treatment: pragmatic, multicentre, randomised controlled trial.BMJ.2025 Jan 29:388:e081474. doi: 10.1136/bmj-2024-081474. (IF:93.6)
2.Junhao Yan#, Yingying Qin#, Han Zhao#, Yun Sun#, Fei Gong#, Rong Li#, Xiaoxi Sun#, Xiufeng Ling#, Hong Li#, … , Heping Zhang, Richard S Legro,Zi-Jiang Chen*. Live Birth with or without Preimplantation Genetic Testing for Aneuploidy.N Engl J Med. 2021 Nov 25;385(22):2047-2058. (IF 176.079)
3.Xuepeng Chen#, Yuwen Ke#, Keliang Wu#, Han Zhao#, Yaoyu Sun, Lei Gao, Zhenbo Liu, Jingye Zhang, Wenrong Tao, Zhenzhen Hou, Hui Liu, Jiang Liu* &Zi-Jiang Chen*. Key role for CTCF in establishing chromatin structure in human embryos.Nature. 2019 Dec;576(7786):306-310. (IF: 69.504)
4.Lei Gao, Keliang Wu, Zhenbo Liu, …, Han Zhao, Jianqiao Liu*,Zi-Jiang Chen*, Jiang Liu*. Chromatin accessibility landscape in human early embryos and its association with evolution.Cell.2018 Mar 22;173(1):248-259.e15.（IF: 66.85）
5.Zhuoning Zou #, Chuanxin Zhang #, Qiuyan Wang #, Zhenzhen Hou #, Zhuqing Xiong, Feng Kong, Qiujun Wang, Jinzhu Song, Boyang Liu, Bofeng Liu, Lijuan Wang, Fangnong Lai, Qiang Fan, Wenrong Tao, Shuai Zhao, Xiaonan Ma, Miao Li, Keliang Wu, Han Zhao*,Zi-Jiang Chen*, Wei Xie*.Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation.Science. 2022 Oct 7;378(6615):abo7923.Science.(IF:56.9)
6.Daimin Wei, Jiayin Liu, Yun Sun, Yuhua Shi, Bo Zhang, Jianqiao Liu,…, Heping Zhang, Richard S Legro, andZi-Jiang Chen*. Frozen versus fresh single blastocyst transfer in ovulatory women: a multicenter, randomized controlled trial.Lancet. 2019 Oct 5;394(10205):1228.(IF: 202.731)
7.Yun Sun#*, Linlin Cui#, Yao Lu#, Jichun Tan#, Xi Dong#, Tianxiang Ni#, Junhao Yan, Yichun Guan, Guimin Hao, Jia-Yin Liu, … Yanzhi Du, Hugo Vankelecom, Heping Zhang,Zi-Jiang Chen*. Prednisone vs Placebo and Live Birth in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization: A Randomized Clinical Trial.JAMA.2023 May 2;329(17):1460-1468. (IF:120.7)
8.Yuhua Shi, Yun Sun, Cuifang Hao, Heping Zhang, Daimin Wei, Yunshan Zhang, Yimin Zhu,…, Richard S. Legro, andZi-Jiang Chen*.Transfer of Fresh versus Frozen Embryosin Ovulatory Women.N Engl J Med.2018 Jan 11; 378:126-36.(IF 176.079)
9.Zi-Jiang Chen*, Yuhua Shi, Yun Sun, Bo Zhang, Xiaoyan Liang,…, Heping Zhang, Richard S. Legro. Fresh versus frozen embryos for infertility in polycystic ovary syndrome.N Engl J Med.2016 Aug 11; 375(6):523-33. (IF 176.079)
10.Yingying Qin, Feng Zhang,Zi-Jiang Chen*. BRCA2 in Ovarian Development and Function.N Engl J Med. 2019 Mar 14;380(11):1086.(IF 176.079)
11.Hanni Ke#, Shuyan Tang#, Ting Guo#, Dong Hou, Xue Jiao, Shan Li, Wei Luo, Bingying Xu, Shidou Zhao, Guangyu Li, Xiaoxi Zhang, Shuhua Xu, Lingbo Wang, Yanhua Wu, Jiucun Wang, Feng Zhang*, Yingying Qin*, Li Jin*,Zi-Jiang Chen*. Landscape of pathogenic mutations in premature ovarian insufficiency.Nat Med.2023 Feb;29(2):483-492. (IF:82.9)
12.Zi-Jiang Chen*, Han Zhao, Lin He, Yuhua Shi, Yingying Qin, Yongyong Shi*, …, Jinlong Ma, Yueran Zhao. Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3.Nat Genet. 2011 Jan; 43(1): 55–59.（IF:41.307）
13.Yongyong Shi, Han Zhao, Yuhua Shi, Yunxia Cao, …, Lin He*, andZi-Jiang Chen*. Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.Nat Genet.2012 Sep; 44(9): 1020-5.（IF:41.307）
14.Keliang Wu, Tailai Chen, Sexin Huang, Cuiqing Zhong, Junhao Yan, Xiaoyu Zhang, Jinsong Li, Yuan Gao*, Han Zhao*andZi-Jiang Chen*. Mitochondrial replacement by pre-pronuclear transfer in human embryos. Cell Res. 2017 Jun; 27(6):834-837. (IF:46.297)
15.Xiaoxue Yuan, Tao Hu, Han Zhao, …, Wanzhu Jin*, andZi-Jiang Chen*.Brown adipose tissue transplantation ameliorates polycystic ovary syndrome.Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2708-13.（IF:12.779）
16.Keliang Wu, Cuiqing Zhong, Tailai Chen, Xiaoyu Zhang, Wenrong Tao, Jingye Zhang, Hongchang Li, Han Zhao*, Jinsong Li* andZi-Jiang Chen*. Polar bodies are efficient donors for reconstruction of human embryos for potential mitochondrial replacement therapy. Cell Res. 2017 Aug; 27(8):1069-1072. (IF:46.297)
17.Honghui Zhang, Tailai Chen, Keliang Wu, Zhenzhen Hou, Shigang Zhao, Chuanxin Zhang, Yuan Gao, Ming Gao,Zi-Jiang Chen*, Han Zhao*. Dominant mutations in CHK1 cause pronuclear fusion failure and zygote arrest that can be rescued by CHK1 inhibitor. Cell Res. 2021 May 6. doi: 10.1038/s41422-021-00507-8.(IF:46.297)
18.Keliang Wu#, Dongdong Fan#, Han Zhao, …Yong Tian*,Zi-Jiang Chen*, Jiang Liu*, and Lei Gao*. Dynamics of histone acetylation during human early embryogenesis. Cell Discov. 2023 Mar 14;9(1):29. doi: 10.1038/s41421-022-00514-y. (IF:33.5)
19.Yuan Gao*, Lizhi Yi, Jianhong Zhan, Lijuan Wang, … Yang Zou, Xuan Gao, Keliang Wu, Jiang Liu*,Zi-Jiang Chen*. A clinical study of preimplantation DNA methylation screening in assisted reproductive technology. Cell Res. 2023 Jun;33(6):483-485. (IF:44.1)
20.Shenli Yuan #, Jianhong Zhan #, Jingye Zhang #, Zhenbo Liu, Zhenzhen Hou, Chuanxin Zhang, Lizhi Yi, Lei Gao*, Han Zhao*, Zi-Jiang Chen*, Jiang Liu*, Keliang Wu*. Human zygotic genome activation is initiated from paternal genome. Cell Discov. 2023 Jan 31;9(1):13. (IF:33.5)
