学习与工作经历：

2009/09-2014/07   山东大学，医学院 博士 

2014/06-2015/5     山东大学齐鲁医院  泌尿外科 医师

2015/06-2022/11     山东大学齐鲁医院  泌尿外科 主治医师

2017/09-2023/09   山东大学齐鲁医学院 遗传学 博士后

2019/06-2021/6     瑞典卡罗琳斯卡医学院 Bioclinicum and Center for Molecular Medicine 博士后  

2022/11-至今   山东大学齐鲁医院  泌尿外科 副主任医师，副教授

研究方向：

代谢重编程和表观遗传学与肾癌进展的研究

学术/社会兼职：

泌尿外科杂志电子版   青年编委

Current Urology杂志 青年编委

山东省亚健康防治协会 泌尿外科分会   副主任委员

山东省激光医学会     泌尿外科分会   常务委员

山东省医师协会       泌尿腔镜委员会 委员兼秘书

获奖荣誉：

本科生课程：

外科学

研究生课程：

82103557   致癌代谢物L-2-HG通过m6A甲基化调控GABPA影响肾癌进展转移的作用及机制研究   国家自然基金青年基金 2021-2024     30万   主持 

ZR2020QH245   槐耳通过调控JMJD6/AR-V9逆转去势抵抗性前列腺癌恩杂鲁胺耐药的机制研究   山东省自然基金青年基金 2021-2024   15万   主持

1.Fang Z,Zhang N, Yuan X, Xing X, Li X, Qin X, Liu Z, Neo S, Liu C, Kong F, Björkholm M, Fan Y, Xu D.GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma.J Exp Clin Cancer Res. 2022 May 12;41(1):173. doi: 10.1186/s13046-022-02382-6. PMID: 35549739; PMCID: PMC9097325.

2.Li X, Liu Z, Xia C, Yan K,Fang Z*,Fan Y*.SETD8 stabilized by USP17 epigenetically activates SREBP1 pathway to drive lipogenesis and oncogenesis of ccRCC.Cancer Lett. 2022 Feb 28;527:150-163. doi: 10.1016/j.canlet.2021.12.018. Epub 2021 Dec 21. PMID: 34942305.

3.Liu Z, Liu C, Yan K, Liu J,Fang Z*,Fan Y*.Huaier Extract Inhibits Prostate Cancer Growth via Targeting AR/AR-V7 Pathway.Front Oncol. 2021 Feb 23;11:615568. doi: 10.3389/fonc.2021.615568. PMID: 33708629; PMCID: PMC7940541.

4.Qin X, Liu Z, Yan K,Fang Z*,Fan Y*.Integral Analysis of the RNA Binding Protein-associated Prognostic Model for Renal Cell Carcinoma.Int J Med Sci. 2021 Jan 1;18(4):953-963. doi: 10.7150/ijms.50704. PMID: 33456353; PMCID: PMC7807188.

5.Zhang G, Li Z, Song D,Fang Z*.Nomograms to predict individual prognosis of patients with squamous cell carcinoma of the urinary bladder.BMC Cancer. 2019 Dec 9;19(1):1200. doi: 10.1186/s12885-019-6430-6. PMID: 31818271; PMCID: PMC6902456.

6.Li Z,Fang Z,Xing N, Zhu S, Fan Y.The effect of CPAP and PDE5i on erectile function in men with obstructive sleep apnea and erectile dysfunction: A systematic review and meta-analysis.Sleep Med Rev. 2019 Dec;48:101217. doi: 10.1016/j.smrv.2019.101217. Epub 2019 Oct 7. PMID: 31715462.

7.Gao Z, Zhang D, Duan Y, Yan L, Fan Y,Fang Z*,Liu Z*.A five-gene signature predicts overall survival of patients with papillary renal cell carcinoma.PLoS One. 2019 Mar 1;14(3):e0211491. doi: 10.1371/journal.pone.0211491. PMID: 30822312; PMCID: PMC6396926.

8.Song D, Jiao W, Gao Z, Liu N, Zhang S, Zong Y,Fang Z*,Fan Y*.Inflammatory myofibroblastic tumor of urinary bladder with severe hematuria: A Case report and literature review.Medicine (Baltimore). 2019 Jan;98(1):e13987. doi: 10.1097/MD.0000000000013987. PMID: 30608442; PMCID: PMC6344176.

9.Zhang G, Wu Y, Zhang J,Fang Z*,Liu Z, Xu Z, Fan Y*.Nomograms for predicting long-term overall survival and disease-specific survival of patients with clear cell renal cell carcinoma.Onco Targets Ther. 2018 Sep 6;11:5535-5544. doi: 10.2147/OTT.S171881. PMID: 30233214; PMCID: PMC6134959.

10.Liu N, Zhang W, Tan J, Zhou J, Yu X, Ren N,Fang Z,Jiao W, Fan Y, Liu C.Adrenal myelolipoma with hyperandrogenemia and schizophrenia.Cancer Manag Res. 2018 Feb 1;10:177-180. doi: 10.2147/CMAR.S145332. PMID: 29440927; PMCID: PMC5798574.