学习经历：

2009.9–2013.12, 山东大学, 细胞生物学, 博士

2006.9–2009.7, 山东大学, 细胞生物学, 硕士

2002.9–2006.7, 山东大学威海分校, 生物技术, 学士

工作经历：

2019.5-至今, 山东大学齐鲁医院血液科研究员/泰山学者青年专家

2016.7-2019.4, 山东大学齐鲁医院血液科助理研究员/副研究员

2013.12-2016.6, 山东大学博士后/基础医学院讲师

研究方向：

围绕恶性血液系统疾病发病耐药机制，从基础研究和学科交叉的角度寻找干预模式和靶点。

学术/社会兼职：

博士生导师，博士后合作导师。中国转化医学联盟理事会理事，山东省医学会临床分析细胞学分会委员，山东省抗癌协会血液肿瘤分会委员，山东省医学伦理学学会交叉科学分会秘书长，山东省医药生物技术学会第二届生物标记与体外诊断技术专业委员会副主任委员，山东省大数据研究会医学分会常务委员，山东省大健康精准医疗产业技术研究院医学伦理委员会委员，《Genomics, Proteomics & Bioinformatics》、《The Innovation Oncology》等期刊青年编委。

获奖荣誉：

2018年入选泰山学者青年专家，2019年入选山东大学青年交叉创新群体。

本科生课程：

《人工智能与血液系统及内分泌系统疾病》

研究生课程：

《血液系统恶性疾病的发病机制、诊断及治疗进展》

骨髓乏氧环境诱导的QKI7乳酸化通过抑制其液-液相分离促进CXCR4蛋白表达和AML细胞骨髓归巢，国家自然科学基金面上项目，主持

靶向造血干细胞及相关疾病的新药创制，山东大学青年交叉科学创新群体

ITP患者巨核细胞中通过抑制JIP3表达调节c-Mpl在细胞膜表面的分布及其机制研究，国家自然科学基金面上项目，主持

“组织者”肿瘤细胞通过诱导SEMA4A表达和紧密连接形成构筑原发性中枢神经系统淋巴瘤免疫屏障及机制研究，山东省自然科学基金面上项目，主持

JIP1与JIP3协同介导TrkB顺轴突转运及其机制研究，国家自然科学基金青年项目，主持

JIP3调控小鼠学习记忆行为的细胞与分子机制研究，中国博士后科学基金特别资助，主持

1. Xiao Jilong#, Xia Yuan#, Yin Fangjing, Shi Ziyu, Meng Guangqiang, Ye Jingjing, Sun Tao*, Ji Chunyan*. Global spatiotemporal distribution characteristics and regional risk stratification model of acute myeloid leukaemia based on molecular genetics and cytogenetic features. British Journal of Haematology.2025 Aug;207(2):395-406.

2. Li Mingying#, Sun Tao#,Chang Mengyuan, Liu Tingting, Feng Lei, Zhang Di, Wu Yuyan, Ma Yuechan, Ma Huixian, Meng Guangqiang, Ji Chunyan*, Ye Jingjing*.Impact of single nucleotide polymorphisms of immunomodulatory factors on treatment response and prognosis in acute myeloid leukemia. Frontiers in Immunology.2025 Mar 31:16:1571332

3. Li Mingying#, Ye Jingjing#, Chang Mengyuan, Feng Lei, Liu Tingting, Zhang Di, Wu Yuyan, Ma Yuechan, Meng Guangqiang, Ji Chunyan*, Sun Tao*. Polymorphisms in immunosuppression-related genes are associated with AML.Frontiers in Immunology. 2025 Feb 5:16:1530510.

4. Ruinan Jia#, Yang Liu#, Jilong Xiao, Yuan Xia, Xin Zhao, Huixian Ma, Jingjing Ye, Zhiyue Zhang,Tao Sun*, Chunyan Ji*.A ROS-Responsive Dual-Targeting Drug Nanocarrier Serving as a GSI Synergist and Ferroptosis Sensitizer for T-Cell Acute Lymphoblastic Leukemia. Advanced Science.2025 Aug;12(31):e05087.

5. Xin Zhao#, Huixian Ma#, Guosheng Li#, Jilong Xiao, Zhiyu Shi, Mingying Li, Xinguang Liu,Tao Sun*, Chunyan Ji*.Adiponectin Assists Thrombopoietic Agents in ITP Treatment by Enhancing Myosin-9/Rab6A-Mediated Trafficking of c-Mpl in MKs. Advanced Science. 2025 Sep;12(34):e03008.

6. Wang DM^#,Sun T^#, Xia Y, Zhao Z, Sheng X, Li SY, Ma YC, Li MY, Su XH, Zhang F, Li P, Ma DX, Ye JJ, Lu F^*, Ji C^*.Homodimer-mediated phosphorylation of C/EBPα-p42 S16 modulates acute myeloid leukaemia differentiation through liquid-liquid phase separation. Nature Communications.2023 Oct 30;14(1):6907.

7. Li M^#, Ye J^#, Xia Y, Li M, Li G, Hu X, Su X, Wang D, Zhao X, Lu F, Li J, Ma D,Sun T^*, Ji C^*. METTL3 mediates chemoresistance by enhancing AML homing and engraftment via ITGA4. Leukemia. 2022 Nov;36(11):2586-2595.

8. Xia Y^#,Sun T^#, Li G, Li M, Wang D, Su X, Ye J^*, Ji C^*. Spatial single cell analysis of tumor microenvironment remodeling pattern in primary central nervous system lymphoma. Leukemia. 2023 Apr 29;37(7):1499-1510.

9. Li M^#, Li M^#, Xia Y, Li G, Su X, Wang D, Ye J, Lu F,Sun T^*, Ji C^*. HDAC1/3-dependent moderate liquid–liquid phase separation of YY1 promotes METTL3 expression and AML cell proliferation. Cell Death & Disease. 2022 Nov 24;13(11):992.

10. Jia R^#,Sun T^#, Zhao X, Li G, Xia Y, Zhou Y, Li W, Li W, Ma D, Ye J^*, Ji M^*, Ji C^*. DEX-Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T-Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy. Advanced Science. 2023 Apr 18:e2205854.

11. Wu Y^#, Li M, Meng G, Ma Y, Ye J,Sun T^*, Ji C^*. Immune checkpoint-related gene polymorphisms are associated with acute myeloid leukemia. Cancer Medicine. 2023 Aug 21.

12. Meng G^#, Li P^#, li M, Wu Y, Ma Y,Sun T^*, Ji C^*. KLK2 single-nucleotide polymorphism rs198977 is associated with increased susceptibility and hyperleukocytosis in AML. Frontiers in Genetics. 2023 Aug 1;14:1218523.

13. Meng G^#, Li M, Xia Y, Wu Y, Ma Y, Ji M, Zhang J, Ye J,Sun T^*, Ji C^*. Mitochondrial apoptosis-related gene polymorphisms are associated with responses to anthracycline-based chemotherapy in acute myeloid leukaemia. Frontiers in Oncology. 2023;13:1179937.

14. Meng S^#, Xia Y^#, Li M, Wu Y, Wang D, Zhou Y, Ma D, Ye J,Sun T^*, Ji C^*. NCBP1 enhanced proliferation of DLBCL cells via METTL3-mediated m6A modification of c-Myc. Scientific Reports. 2023 May 27;13(1):8606.

15. Jia R^#, Ji M^#, Li G, Xia Y, Guo S, Li P, Sun Y, Lu F, Zhang J, Zang S, Yan S, Ye J, Xue F, Ma D,Sun T^*, Ji C^*. Subclones of bone marrow CD34+ cells in acute myeloid leukemia at diagnosis confer responses of patients to induction chemotherapy. Cancer. 2022 Nov 15;128(22):3929-3942.

16. Su X^#,Sun T^#, Li M, Xia Y, Li M, Wang D, Lu F, Ye J, Ji C^*. Lkb1 aggravates diffuse large B-cell lymphoma by promoting the function of Treg cells and immune escape. Journal of Translational Medicine. 2022 Aug 19;20(1):378.