学习与工作经历：

2019.3至今      山东大学基础医学院组织学与胚胎学系  教授

2014.7-2019.1   美国加州大学圣塔芭芭拉分校          博士后

2008.9-2014.5   美国罗格斯新泽西州立大学            博士

2004.9-2008.7   浙江大学                            学士

研究方向：

1. 器官发育与再生中的大小调控

2. 肿瘤的复发与转移的分子机制

学术/社会兼职： 

获奖荣誉：

山东大学齐鲁青年学者

本科生课程：

模式动物原理与技术、发育生物学

研究生课程：

干细胞研究进展、细胞信号转导与疾病、细胞死亡与中枢神经系统疾病

1. 以果蝇翅成虫盘为模型研究Ciz1在器官生长调控中的作用及其机制。国家自然科学基金面上项目，2023.1-2026.12，54万，主持

2. 胚系遗传肢体发育缺陷新基因新变异致病机制研究。国家重点研发计划子课题，2022.11-2026.11，299万，骨干

3. 细胞重生在果蝇翅成虫盘再生中的作用和机制研究。国家自然科学基金面上项目，2020.1-2023.12，60万，主持

4. 细胞重生在乳腺癌化疗后复发和转移中的作用和机制研究。国家自然科学基金青年项目，2020.1-2022.12，20.5万，主持

1.Ma Y, Liu X, Zhou M, Sun W, Jiang B, Liu Q, Wang M, Zou Y, Liu Q, Gong Y^#,Sun G^#. CUL4B mutations impair human cortical neurogenesis through PP2A-dependent inhibition of AKT and ERK.Cell Death Dis.2024, 15(2):121. (#共同通讯)

2.Sun G. Death and survival from executioner caspase activation.Semin Cell Dev Biol. 2024, 156:66-73.

3.Wang R, Wang Y, Liu X, Liu M, Sun L, Pan X, Hu H, Jiang B, Zou Y, Liu Q, Gong Y, Wang M^#,Sun G^#. Anastasis enhances metastasis and chemoresistance of colorectal cancer cells through upregulating cIAP2/NFkB signaling.Cell Death Dis. 2023, 14(6):388. (#共同通讯)

4.Wang Y, Wang R, Liu X, Liu M, Sun L, Pan X, Hu H, Jiang B, Zou Y, Liu Q, Gong Y, Wang M^#,Sun G^#. Chemotherapy-induced executioner caspase activation increases breast cancer malignancy through epigenetic de-repression of CDH12.Oncogenesis. 2023, 12(1):34. (#共同通讯)

5.Song Y, Jin S,Sun G^#, Gong Y^#. Cullin 4B-RING E3 ligase complex in immune cell differentiation and function.Cell Mol Immunol. 2023,20(10): 1254-1256. (#共同通讯)

6.Jin S, Song Y, Zhou L, Jiang W, Qin L, Wang Y, Yu R, Liu Y, Diao Y, Zhang F, Liu K, Li P, Hu H, Jiang B, Tang W, Yi F, Gong Y, Liu G^#,Sun G^#. Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis.Cell Rep. 2023, 42(6): 112550. (#共同通讯)

7.Sun L, Yao C, Li X, Wang Y, Wang R, Wang M, Liu Q, Montell DJ, Shao C, Gong Y,Sun G. Anastasis confers ovarian cancer cells increased malignancy through elevated p38 MAPK activation.Cell Death Differ. 2023, 30(3): 809-824.

8.Sun G^#, Ding XA, Argaw Y, Guo X, Montell DJ^#. Akt1 and dCIZ1 promote cell survival from apoptotic caspase activation during regeneration and oncogenic overgrowth.Nat Commun.2020, 11(1): 5726 (#共同通讯)

9.Sun G, Montell DJ. Q&A: Cellular near death experience-what is anastasis?BMC Biol.2017, 15 (1):92.

10.Sun G, Guzman E, Balasanyan V, Conner CM, Wong K, Zhou HR, Kosik K, Montell DJ. A molecular signature for anastasis, recovery from the brink of apoptotic cell death.J Cell Biol. 2017, 216 (10): 3355-3368.

11.Ding AX*,Sun G*, Argaw YG, Wong JO, Easwaran S, Montell DJ. CasExpress reveals widespread and diverse patterns of cells survival of caspase-3 activation during development in vivo.Elife2016, 5:e10936. (*共同第一)